Click [here](https://img1.wsimg.com/blobby/go/07e8358d-95f4-491a-894f-2f68b592c366/PRNANO%207(1)%20Cover.pdf) to download a hi-res PDF copy of the cover page ##FEATURE ARTICLE: **Research Article** Narsineni L, Hakim A, Guido B, and Foldvari M, Evaluation of transfection with gemini nanoparticles for retinal neuroprotection in a dynamic microfluidic cell culture system, [Precis. Nanomed. 2024, 7(1):1264-1278](https://doi.org/10.33218/001c.94464) POTENTIAL CLINICAL SIGNIFICANCE _From the Clinical Editor:_ The authors describe a new microfluidics technique using nanoparticles for increasing Transfection Efficiency providing a useful tool for retinal and nerve cell restoration. [ALTMETRIC and CITATIONS](https://precisionnanomedicine.net/prnano-1252024) ARTICLES **Discussion** Thomas FJ, Khan MAQS, Khan RA, and Patel SV, Effectiveness of Lecanemab on Alzheimer’s Disease, [Precis. Nanomed. 2023, 7(1):1211-1220](https://doi.org/10.33218/001c.92098) CLINICAL SIGNIFICANCE _From the Clinical Editor:_ This study offers a comprehensive overview of the efficacy and safety of lecanemab, a monoclonal antibody, targeting AD pathology. focusing on its binding properties and encouraging results from clinical trials. [ALTMETRIC and CITATIONS](https://precisionnanomedicine.net/prnano-1142023) **Research Article** Anna IM, Gowd GS, Ashokan A, Manohar M, Nair SV, Bhakoo K, and Koyakutty M, Magnetic resonance imaging of mesenchymal stem cell – migration towards glioblastoma using nano-calcium phosphate contrast agent, [Precis. Nanomed. 2024, 7(1):1252-1263](https://doi.org/10.33218/001c.94159) POTENTIAL CLINICAL SIGNIFICANCE _From the Clinical Editor:_ This study describes the potential of iron nano-contrast agent for labeling stem cells and tracking their migration towards solid brain tumors using MRI to improve anti-glioma therapies. [ALTMETRIC and CITATIONS](https://precisionnanomedicine.net/prnano-1162023) **Reviews** Abdelmonem M, Albert EL, Maha A. Alhadad AA, and Abdullah CAC, Plant-Polyphenol-Mediated Synthesis of Magnetic Biocompatible Iron Oxide Nanoparticles for Diagnostic Imaging and Management of Neurodegenerative Diseases, [Precis. Nanomed. 2024, 7(1):1233-1251](https://doi.org/10.33218/001c.92424) CLINICAL SIGNIFICANCE _From the Clinical Editor:_ This comprehensive review describes iron oxide nanoparticles as effective targeted nanocarriers for neuroprotective therapeutics and novel diagnostic tools for various neurodegenerative diseases, such as Alzheimer's, Parkinson's, and glioblastoma. [ALTMETRIC and CITATIONS](https://precisionnanomedicine.net/prnano-992023) Rajendran Sh, Sundararajan P, Ashi Awasthi A, Rajendran Su, Nanorobotics in Medicine: A Systematic Review of Advances, Challenges, and Future Prospects with a focus on Cell Therapy, Invasive Surgery, and Drug Delivery, [Precis. Nanomed. 2024, 7(1):1221-1232](https://doi.org/10.33218/001c.92224) CLINICAL SIGNIFICANCE _From the Clinical Editor:_ Emergence of nanorobotics is owed partly to advances in nanotechnology/nanomedicine and potentially diverse applications, including cellular manipulation, targeted drug delivery, disease diagnosis, and surgery at the microscopic level. In this review, the authors describe and discuss the various uses of nanorobots in the medical field, pointing to a direction for future research and development, specifically in niches such as laparoscopic surgery, drug delivery, and cell manipulation. [ALTMETRIC and CITATIONS](https://precisionnanomedicine.net/prnano-1102023)

Effectiveness of Lecanemab on Alzheimer’s Disease

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